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Table 2 Diagnostic values of the criteria and non-criteria aPLs

From: “Non-criteria” antiphospholipid antibodies add value to antiphospholipid syndrome diagnoses in a large Chinese cohort

Parameters

Sen

Spe

PPV

NPV

PLR

NLR

OR (95% CI)

Youden index

LAC

0.4716

0.9808

0.9568

0.6732

24.6034

0.5387

45.67 (19.7–105.9)

1.4524

aCL IgA

0.3227

0.9617

0.8835

0.6118

8.417

0.7043

11.95 (6.37–22.41)

1.2844

aCL IgG

0.5993

0.9425

0.9037

0.723

10.421

0.4252

24.51 (14.4–41.73)

1.5418

aCL IgM

0.1525

0.9808

0.8776

0.5623

7.9545

0.8641

9.21 (3.85–21.99)

1.1333

aCL IgG/IgM

0.6277

0.9265

0.885

0.7342

8.5416

0.4019

21.25 (13.04–34.64)

1.5542

aCL IgA/G/M

0.6418

0.9105

0.866

0.7383

7.1749

0.3933

18.24 (11.54–28.84)

1.5523

aβ2GPI IgA

0.2979

0.9776

0.9231

0.6071

13.3191

0.7182

18.55 (8.4–40.92)

1.2755

aβ2GPI IgG

0.6702

0.9137

0.875

0.7546

7.7695

0.3609

21.53 (13.51–34.31)

1.5839

aβ2GPI IgM

0.1383

0.9776

0.8478

0.5574

6.1839

0.8814

7.02 (3.08–15.96)

1.1159

aβ2GPI D1

0.489

0.9712

0.9366

0.6862

17.0053

0.5262

32.32 (15.98–65.36)

1.4602

aβ2GPI IgG/M

0.6879

0.9073

0.87

0.7634

7.425

0.3439

21.59 (13.66–34.12)

1.5952

aΒ2GPI IgA/G/M

0.695

0.9073

0.8711

0.7676

7.5016

0.3361

22.32 (14.11–35.3)

1.6023

aΒ2GPI IgG/M/D1

0.6949

0.9042

0.863

0.7732

7.2496

0.3375

21.48 (13.61–33.9)

1.5991

aΒ2GPI IgA/G/M/D1

0.7022

0.9042

0.8643

0.7775

7.3263

0.3294

22.24 (14.08–35.14)

1.6064

aPSPT IgG

0.6213

0.9465

0.9135

0.7332

11.611

0.4001

29.02 (16.58–50.81)

1.5678

aPSPT IgM

0.636

0.8395

0.7828

0.7171

3.9619

0.4336

9.14 (6.15–13.57)

1.4755

aPSPT IgG/M

0.7978

0.8127

0.7949

0.8154

4.2597

0.2488

17.12 (11.31–25.92)

1.6105

aCL IgG/M/aΒ2GPI IgG/M/LAC

0.7872

0.8626

0.8377

0.8182

5.7303

0.2467

23.23 (15.11–35.71)

1.6498

aCL IgA/G/M/aΒ2GPI IgA/G/M/LAC

0.7943

0.8594

0.8358

0.8226

5.6505

0.2393

23.61 (15.36–36.3)

1.6537

aCL IgG/M/aΒ2GPI IgG/M/D1/LAC

0.7831

0.8594

0.8288

0.8201

5.5706

0.2524

22.07 (14.36–33.92)

1.6425

aPSPT IgG/M/aCL IgG/M/aΒ2GPI IgG/M/LAC

0.8897

0.7592

0.7707

0.8833

3.6948

0.1453

25.43 (16.01–40.4)

1.6489

aPSPT IgG/aCL IgA/aΒ2GPI IgA/G/LAC

0.8493

0.8763

0.8619

0.8647

6.863

0.172

39.9 (24.73–64.37)

1.7256

aPSPT IgG/aCL IgG/LAC

0.8235

0.8997

0.8819

0.8486

8.2078

0.1962

41.84 (25.65–68.26)

1.7232

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Arthritis Research & Therapy

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