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Table 2 Diagnostic values of the criteria and non-criteria aPLs

From: “Non-criteria” antiphospholipid antibodies add value to antiphospholipid syndrome diagnoses in a large Chinese cohort

ParametersSenSpePPVNPVPLRNLROR (95% CI)Youden index
LAC0.47160.98080.95680.673224.60340.538745.67 (19.7–105.9)1.4524
aCL IgA0.32270.96170.88350.61188.4170.704311.95 (6.37–22.41)1.2844
aCL IgG0.59930.94250.90370.72310.4210.425224.51 (14.4–41.73)1.5418
aCL IgM0.15250.98080.87760.56237.95450.86419.21 (3.85–21.99)1.1333
aCL IgG/IgM0.62770.92650.8850.73428.54160.401921.25 (13.04–34.64)1.5542
aCL IgA/G/M0.64180.91050.8660.73837.17490.393318.24 (11.54–28.84)1.5523
aβ2GPI IgA0.29790.97760.92310.607113.31910.718218.55 (8.4–40.92)1.2755
aβ2GPI IgG0.67020.91370.8750.75467.76950.360921.53 (13.51–34.31)1.5839
aβ2GPI IgM0.13830.97760.84780.55746.18390.88147.02 (3.08–15.96)1.1159
aβ2GPI D10.4890.97120.93660.686217.00530.526232.32 (15.98–65.36)1.4602
aβ2GPI IgG/M0.68790.90730.870.76347.4250.343921.59 (13.66–34.12)1.5952
aΒ2GPI IgA/G/M0.6950.90730.87110.76767.50160.336122.32 (14.11–35.3)1.6023
aΒ2GPI IgG/M/D10.69490.90420.8630.77327.24960.337521.48 (13.61–33.9)1.5991
aΒ2GPI IgA/G/M/D10.70220.90420.86430.77757.32630.329422.24 (14.08–35.14)1.6064
aPSPT IgG0.62130.94650.91350.733211.6110.400129.02 (16.58–50.81)1.5678
aPSPT IgM0.6360.83950.78280.71713.96190.43369.14 (6.15–13.57)1.4755
aPSPT IgG/M0.79780.81270.79490.81544.25970.248817.12 (11.31–25.92)1.6105
aCL IgG/M/aΒ2GPI IgG/M/LAC0.78720.86260.83770.81825.73030.246723.23 (15.11–35.71)1.6498
aCL IgA/G/M/aΒ2GPI IgA/G/M/LAC0.79430.85940.83580.82265.65050.239323.61 (15.36–36.3)1.6537
aCL IgG/M/aΒ2GPI IgG/M/D1/LAC0.78310.85940.82880.82015.57060.252422.07 (14.36–33.92)1.6425
aPSPT IgG/M/aCL IgG/M/aΒ2GPI IgG/M/LAC0.88970.75920.77070.88333.69480.145325.43 (16.01–40.4)1.6489
aPSPT IgG/aCL IgA/aΒ2GPI IgA/G/LAC0.84930.87630.86190.86476.8630.17239.9 (24.73–64.37)1.7256
aPSPT IgG/aCL IgG/LAC0.82350.89970.88190.84868.20780.196241.84 (25.65–68.26)1.7232