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Table 3 Association analysis of rs2231142, rs10011796 (ABCG2) and rs11942223 (SLC2A9) gout risk alleles with the number of self-reported gout flares in the previous year by gout patients

From: Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout

SNP/risk allele

N

β (SE)*

P

rs2231142/T

 European gout

921

− 0.019 (0.479)

0.97

 Western Polynesian gout

359

2.54 (0.965)

8.9E−03

 Eastern Polynesian gout

481

1.69 (1.061)

0.11

Polynesian meta-analysis

840

2.16 (0.714)

2.5E−03

rs10011796/T

 European gout

920

0.29 (0.396)

0.47

 Western Polynesian gout

359

0.46 (0.982)

0.64

 Eastern Polynesian gout

481

− 1.02 (0.638)

0.11

Polynesian meta-analysis

840

- 0.58 (0.535)

0.28

rs11942223/T

 European gout

924

− 0.11 (0.596)

0.85

 Western Polynesian gout

359

1.80 (3.122)

0.56

 Eastern Polynesian gout

481

2.53 (1.440)

0.080

Polynesian meta-analysis

840

2.40 (1.308)

0.067

  1. *European sample set adjusted by age and sex. Polynesian sample sets additionally adjusted by PCs 1–10