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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1

Fig. 6

a Immunofluorescence intensity analysis of Spry1 and ACAN expression in MCCs. MCCs were transfected with miR-21-5p mimic or miR-21-5p inhibitor and then stimulated with IL-1β for 24 h. Fluorescence micrographs of Spry1 are shown in red (b), ACAN (c) in green, and nuclei in blue. Data are represented as the means ± standard deviation (n = 3). Asterisk (*): compared with the NC group. Hash (##): compared with the IL-1β + NC group. Data are represented as the means ± standard deviation (n = 3). *P < 0.05, #P < 0.05, ##P < 0.05. NS, not significant. Scale bar, 50 μm

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