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Table 2 Results of the ROC analysis of the ability of IFN5 score to predict various disease outcomes

From: The baseline interferon signature predicts disease severity over the subsequent 5 years in systemic lupus erythematosus

Outcome

Optimal IFN5 cut-off

Sensitivity

Specificity

PPV

NPV

No LLDAS

66.45

83.8

46.7

71.4

65.3

Adjusted mean prednisone > 6

64.26

64.4

67.2

69.1

62.3

≥ 2 flares

64.79

63.6

64.5

63.6

64.5

New immunosuppressive

60.00

81.3

41.7

46.7

77.8

  1. Abbreviations: LLDAS lupus low disease activity state, PPV positive predictive value, NPV negative predictive value