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Table 3 The concomitant use of cDMARD/steroid medications with biologics

From: Treatment persistence of biologics among patients with psoriatic arthritis

 

Treatment periods

P value

Adalimumab

Etanercept

Infliximab

Ustekinumab

Golimumab

Secukinumab

Concomitant MTX

No

642

75.7%

807

81.6%

159

68.2%

210

87.5%

267

75.0%

244

83.6%

0.001

Yes

206

24.3%

182

18.4%

74

31.8%

30

12.5%

89

25.0%

48

16.4%

Concomitant other cDMARDs

No

783

92.3%

919

92.9%

210

90.1%

221

92.1%

311

87.4%

264

90.4%

0.03

Yes

65

7.7%

70

7.1%

23

9.9%

19

7.9%

45

12.6%

28

9.6%

MTX before

No

163

19.2%

177

17.9%

47

20.2%

43

17.9%

44

12.4%

40

13.7%

0.03

Yes

685

80.8%

812

82.1%

186

79.8%

197

82.1%

312

87.6%

252

86.3%

cDMARDs before

No

322

38.0%

319

32.3%

106

45.5%

103

42.9%

101

28.4%

102

34.9%

0.001

Yes

526

62.0%

670

67.7%

127

54.5%

137

57.1%

255

71.6%

190

65.1%

GC

No

510

60.1%

633

64.0%

132

56.7%

141

58.8%

195

54.8%

196

67.1%

0.03

Yes

338

39.9%

356

36.0%

101

43.3%

99

41.3%

161

45.2%

96

32.9%

  1. cDMARDs conventional disease-modifying anti-rheumatic drugs, GC glucocorticosteroids, MTX methotrexate