Skip to main content
Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Is gene expression among women with rheumatoid arthritis dysregulated during a postpartum flare?

Fig. 3

Some genes whose expression are modulated postpartum in healthy women demonstrate dysregulated expression during the RA postpartum flare. a Log2-transformed fold-changes in gene expression from the 3rd trimester (T3) to 3 months postpartum (PP3) are plotted for healthy women (x-axis) and for women with RA who flared postpartum (RAFlare) (y-axis). Several genes (n = 33) whose expression levels decreased significantly from T3 to PP3 among healthy women showed a significantly smaller decrease (or increase in the case of NKX3-1) in expression among the women with RA. b Log2-transformed fold-changes in gene expression for between-group (RAFlare vs. healthy) analyses at PP3 (x-axis) are plotted against those at T3 (y-axis). The 33 genes that had a smaller decrease (or increase) in expression in RAFlare postpartum (PP3 vs. T3 shown in a) did not have significantly different expression levels between the 2 groups of women at T3. At PP3, however, they had significantly (2–10-fold) higher (or lower) expression levels in RAFlare compared to healthy women

Back to article page