Table 2 The genes that were differentially expressed between the third trimester and the time point of maximal disease activity postpartum (PPmax) during the RA flare were enriched in these Gene Ontology (GO) terms
From: Is gene expression among women with rheumatoid arthritis dysregulated during a postpartum flare?
GO term | Description | Enrichment ratio | q value |
|---|---|---|---|
GO:0035744 | T helper 1 cell cytokine production | 34.7 | 5.6E−04 |
GO:0002227 | Innate immune response in mucosa | 19.3 | 7.7E−04 |
GO:0035456 | Response to interferon-beta | 10.5 | 9.1E−03 |
GO:0006778 | Porphyrin-containing compound metabolic process | 9.4 | 1.4E−02 |
GO:0031640 | Killing of cells of other organism | 9.3 | 4.5E−04 |
GO:0015701 | Bicarbonate transport | 8.3 | 2.2E−02 |
GO:0019730 | Antimicrobial humoral response | 8.2 | 2.5E−06 |
GO:0150076 | Neuroinflammatory response | 7.2 | 3.5E−02 |
GO:0030218 | Erythrocyte differentiation | 7.0 | 1.3E−04 |
GO:0002444 | Myeloid leukocyte mediated immunity | 7.0 | < 2.2e−16 |
GO:0051851 | Modification by host of symbiont morphology or physiology | 6.9 | 6.5E−03 |
GO:0055076 | Transition metal ion homeostasis | 6.2 | 1.4E−04 |
GO:0097530 | Granulocyte migration | 6.2 | 1.5E−04 |
GO:0050729 | Positive regulation of inflammatory response | 5.3 | 2.8E−03 |
GO:1903900 | Regulation of viral life cycle | 5.1 | 3.2E−03 |
GO:0008645 | Hexose transmembrane transport | 4.6 | 4.3E−02 |
GO:0071222 | Cellular response to lipopolysaccharide | 4.3 | 3.1E−03 |
GO:0010950 | Positive regulation of endopeptidase activity | 4.3 | 1.1E−02 |
GO:0002700 | Regulation of production of molecular mediator of immune response | 4.1 | 4.4E−02 |
GO:0052548 | Regulation of endopeptidase activity | 3.2 | 2.2E−03 |