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Table 2 The common genes identified by both TWAS and microarray expression data

From: Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis

Genes CHR HSQ BEST.GWAS.ID NSNP PTWAS Regulation*
ANXA5e 4 0.449 rs7691220 439 0.04665 Down
AP4B1y 1 0.092 rs2476601 463 0.00849 Down
ATICt 2 0.335 rs4673928 473 0.01130 Down
C12orf65t 12 0.067 rs1727323 335 0.00191 Down
CMAHn 6 0.081 rs6906654 682 0.01422 Down
PDHBy 3 0.116 rs13315591 435 0.02839 Down
RUNX3y 1 0.044 rs4520361 372 0.03460 Down
SBF1y 22 0.115 rs5771362 303 0.01867 Down
SH2B3y 12 0.046 rs4346023 243 0.00345 Down
STK38y 6 0.089 rs7764323 567 0.00056 Down
TMEM43y 3 0.049 rs1106087 556 0.03760 Down
XPNPEP1n,y 10 0.016 rs10787226 321 0.04826 Down
KIAA1530n 4 0.189 rs3755963 345 0.00462 Up
NUFIP2n 17 0.018 rs2041156 345 0.00519 Up
PPP2R3Cn,y 14 0.060 rs10162419 384 0.00072 Up
RAB24e 5 0.369 rs4976688 299 0.03134 Up
STX6y 1 0.103 rs1538620 464 0.00116 Up
TLR5n 4 0.449 rs7691220 439 0.04665 Up
  1. CHR chromosome, HSQ heritability of the gene, BEST.GWAS.ID rsID of the most significant GWAS SNP in locus, NSNP number of SNPs in the locus, PTWAS TWAS P value. *Presents the regulation of gene in genome-wide transcriptional profiles measured on microarrays. e, t, n, yMean the genes were identified by TWAS in EL, TF, NBL, and YBL, respectively
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