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Table 2 Potential clinical applications of circRNAs in OA

From: Circular RNAs in osteoarthritis: indispensable regulators and novel strategies in clinical implications

CircRNA Sample Detection method Expression Parameter Application Ref
hsa_circ_0032131 peripheral blood qRT-PCR AUC (0.8455) diagnostic biomarker [108]
hsa_circ_0020014 peripheral blood qRT-PCR AUC (0.6415) diagnostic biomarker [109]
ciRS-7 peripheral blood qRT-PCR NA diagnostic biomarker [88]
hsa_circ_0104595 synovial fluid microarray analysis, qRT-PCR AUC (0.708) diagnostic biomarker [110]
hsa_circ_0104873 synovial fluid microarray analysis, qRT-PCR AUC (0.683) diagnostic biomarker [110]
hsa_circ_0101251 synovial fluid microarray analysis, qRT-PCR AUC (0.754) diagnostic biomarker [110]
  1. ↑upregulation, ↓downregulation, AUC area under curve