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Table 2 Cross-sectional associations between OA-related MRI features and weight-bearing pain

From: Association of subchondral bone marrow lesion localization with weight-bearing pain in people with knee osteoarthritis: data from the Osteoarthritis Initiative

  Spearman’s r p Β1 (95% CI) p Β2 (95% CI) p
Total BML score 0.34 < 0.001** 0.08 (0.04–0.11) < 0.001** 0.07 (0.02–0.11) 0.005**
 Medial FT joint 0.29 < 0.001** 0.10 (0.04–0.16) 0.001** 0.08 (0.02–0.16) 0.02*
 Lateral FT joint 0.09 0.003** −0.01 (− 0.18–0.15) 0.87 − 0.03 (− 0.19–0.14) 0.74
 Medial PF joint 0.03 0.35 0.06 (− 0.06–0.17) 0.32 0.06 (− 0.06–0.18) 0.31
 Lateral PF joint 0.13 < 0.001** 0.14 (0.05–0.23) 0.003** 0.13 (0.03–0.23) 0.01*
 Subspinous region 0.18 < 0.001** −0.04 (− 0.21–0.14) 0.69 − 0.06 (− 0.24–0.12) 0.53
Articular cartilage score 0.32 < 0.001** 0.05 (0.01–0.1) 0.03* 0.02 (− 0.01–0.05) 0.25
Osteophytes score 0.26 < 0.001** 0.04 (0.01–0.07) 0.01* 0.01 (− 0.01–0.03) 0.46
Hoffa’s synovitis score 0.18 < 0.001** 0.3 (0.03–0.60) 0.03* −0.03 (− 0.21–0.15) 0.72
Effusion score 0.24 < 0.001** 0.4 (0.13–0.59) 0.002** 0.08 (−0.06–0.22) 0.26
Medial meniscus extrusion score 0.22 < 0.001** 0.15 (−0.05–0.36) 0.14 0.03 (−0.12–0.13) 0.96
  1. B1: OA-related MRI features adjusted for non-weight-bearing pain, age, sex, and BMI. BML subscores were in addition adjusted for BML at the other four joint compartments. B2: OA-related MRI features adjusted for non-weight-bearing pain, age, sex, BMI, the other OA-related MRI features, and anterior cruciate ligament tears. BML subscores were in addition adjusted for BML at the other four joint compartments.*p < 0.05, ** p < 0.01
  2. BML bone marrow lesion, FT femorotibial, PF patellofemoral