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Table 3 Percent decrease of cytokines and chemokines in serum

From: A bioavailable form of curcumin, in combination with vitamin-D- and omega-3-enriched diet, modifies disease onset and outcomes in a murine model of collagen-induced arthritis

Cytokine % Decrease compared to mean abundance in CIA mice on normal diet
CIA + CUR CIA + VO CIA + VO + CUR
% Decrease p value % Decrease p value % Decrease p value
IFNγ 58 ± 7.3 p < 0.0003 55 ± 4.1 p < 0.0003 82 ± 3.3 p < 0.0001
TNF 45 ± 3.6 p < 0.0002 36 ± 2.3 p < 0.0002 69 ± 2.8 p < 0.0002
IL-1β 73 ± 2.6 p < 0.001 34 ± 5.3 p < 0.0015 75 ± 3.1 p < 0.0001
IL-6 77 ± 2.7 p < 0.002 16 ± 8.4 p < 0.211 77 ± 3.0 p < 0.002
IL-33 76 ± 4.8 p < 0.004 70 ± 4.8 p < 0.001 61 ± 6.8 p < 0.005
IL-15 75 ± 6.6 p < 0.0003 91 ± 2.5 p < 0.097 81 ± 2.9 p < 0.0003
IL-16 47 ± 6.3 p < 0.0005 20 ± 6.2 p < 0.0002 60 ± 3.4 p < 0.0002
IL-10 46 ± 6.3 p < 0.041 37 ± 3.7 p < 0.002 51 ± 4.4 p < 0.0002
MCP-1 36 ± 5.9 p < 0.0003 22 ± 2.9 p < 0.021 55 ± 3.1 p < 0.0003
KC/GRO 54 ± 8.2 p < 0.0002 16 ± 8.0 p < 0.112 67 ± 3.8 p < 0.0002
IP-10 59 ± 4.9 p < 0.001 40 ± 1.9 p < 0.001 62 ± 3.9 p < 0.0001
MIP-1α 38 ± 5.8 p < 0.001 30 ± 4.8 p < 0.031 59 ± 3.4 p < 0.0015