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Table 4 Diagnostic performance of qDESS MRI for mild, moderate, and severe synovitis

From: Detection of knee synovitis using non-contrast-enhanced qDESS compared with contrast-enhanced MRI

Synovitis grade based on CE-MRI

AUC (std. error)

Cut-off value of whole-joint synovitis sum score [24]

TP

TN

FP

FN

Sensitivity (95%CI)

Specificity (95%CI)

PPV (95%CI)

NPV (95%CI)

Mild or higher (n = 20)

0.98 (0.02)

≥ 5

20

10

1

0

1.00 (0.80–1.00)

0.91 (0.57–1.00)

0.95 (0.74–1.00)

1.00 (0.66–1.00)

Moderate or higher (n = 11)

0.98 (0.02)

≥ 9

8

20

0

3

0.73 (0.39–0.93)

1.00 (0.80–1.00)

1.00 (0.60–1.00)

0.87 (0.65–0.97)

Severe (n = 5)

0.96 (0.03)

≥ 13

0

26

0

5

0 (0–0.54)

1.00 (0.84–1.00)

0.84 (0.66–0.94)

  1. AUC area under the curve, TP true positive, TN true negative, FP false positive, FN false negative, PPV positive predictive value, NPV negative predictive value