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Table 4 Diagnostic performance of qDESS MRI for mild, moderate, and severe synovitis

From: Detection of knee synovitis using non-contrast-enhanced qDESS compared with contrast-enhanced MRI

Synovitis grade based on CE-MRI AUC (std. error) Cut-off value of whole-joint synovitis sum score [24] TP TN FP FN Sensitivity (95%CI) Specificity (95%CI) PPV (95%CI) NPV (95%CI)
Mild or higher (n = 20) 0.98 (0.02) ≥ 5 20 10 1 0 1.00 (0.80–1.00) 0.91 (0.57–1.00) 0.95 (0.74–1.00) 1.00 (0.66–1.00)
Moderate or higher (n = 11) 0.98 (0.02) ≥ 9 8 20 0 3 0.73 (0.39–0.93) 1.00 (0.80–1.00) 1.00 (0.60–1.00) 0.87 (0.65–0.97)
Severe (n = 5) 0.96 (0.03) ≥ 13 0 26 0 5 0 (0–0.54) 1.00 (0.84–1.00) 0.84 (0.66–0.94)
  1. AUC area under the curve, TP true positive, TN true negative, FP false positive, FN false negative, PPV positive predictive value, NPV negative predictive value