Table 5 Diagnostic performance of qDESS MRI for mild, moderate, and severe synovitis using adapted cut-offs values of whole-joint synovitis sum score
From: Detection of knee synovitis using non-contrast-enhanced qDESS compared with contrast-enhanced MRI
Synovitis grade based on CE-MRI | AUC (std. error) | Optimized cut-off value of whole-joint synovitis sum score | TP | TN | FP | FN | Sensitivity (95%CI) | Specificity (95%CI) | PPV (95%CI) | NPV (95%CI) |
|---|---|---|---|---|---|---|---|---|---|---|
Mild or higher (n = 20) | 0.98 (0.02) | ≥ 4 | 20 | 10 | 1 | 0 | 1.00 (0.80–1.00) | 0.91 (0.57–1.00) | 0.95 (0.74–1.00) | 1.00 (0.66–1.00) |
Moderate or higher (n = 11) | 0.98 (0.02) | ≥ 6 | 11 | 18 | 2 | 0 | 1.00 (0.68–1.00) | 0.90 (0.67–0.98) | 0.85 (0.54–0.97) | 1.00 (0.78–1.00) |
Severe (n = 5) | 0.96 (0.03) | ≥ 9 | 5 | 23 | 3 | 0 | 1.00 (0.46–1.00) | 0.89 (0.69–0.97) | 0.63 (0.26–0.90) | 1.00 (0.82–1.00) |