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Table 5 Diagnostic performance of qDESS MRI for mild, moderate, and severe synovitis using adapted cut-offs values of whole-joint synovitis sum score

From: Detection of knee synovitis using non-contrast-enhanced qDESS compared with contrast-enhanced MRI

Synovitis grade based on CE-MRI AUC (std. error) Optimized cut-off value of whole-joint synovitis sum score TP TN FP FN Sensitivity (95%CI) Specificity (95%CI) PPV (95%CI) NPV (95%CI)
Mild or higher (n = 20) 0.98 (0.02) ≥ 4 20 10 1 0 1.00 (0.80–1.00) 0.91 (0.57–1.00) 0.95 (0.74–1.00) 1.00 (0.66–1.00)
Moderate or higher (n = 11) 0.98 (0.02) ≥ 6 11 18 2 0 1.00 (0.68–1.00) 0.90 (0.67–0.98) 0.85 (0.54–0.97) 1.00 (0.78–1.00)
Severe (n = 5) 0.96 (0.03) ≥ 9 5 23 3 0 1.00 (0.46–1.00) 0.89 (0.69–0.97) 0.63 (0.26–0.90) 1.00 (0.82–1.00)
  1. AUC area under the curve, TP true positive, TN true negative, FP false positive, FN false negative, PPV positive predictive value, NPV negative predictive value