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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Lymphatic muscle cells contribute to dysfunction of the synovial lymphatic system in inflammatory arthritis in mice

Fig. 1

Increased diameters and reduced branch points of capillary lymphatic vessels in TNF-Tg mice. a Schematic illustration shows the experimental design; ankle tissues from 1-, 2.5-, and 5-month-old TNF-Tg mice and WT littermates were subjected to whole-mount immunofluorescence staining with an LYVE-1 antibody to identify capillary LVs. b Representative images show dilated LVs in 2.5- and 5-month old TNF-Tg mice (arrows). c Quantification of diameters and branch points. Values are mean ± SD. n = 8–9 legs from 4 to 7 mice per group. *p < 0.05 by the Student t test

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