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Table 1 Population characteristics and their comparison among patients with and without significant RP

From: Markers of disease severity and positive family history are associated to significant risk perception in rheumatoid arthritis, while compliance with therapy is not: a cross-sectional study in 415 Mexican outpatients

Characteristics

Entire population, N = 415

Patients with significant RP, N = 94

Patients without significant RP, N = 321

p

Socio-demographic

 Female sex1

387 (93.3)

93 (98.9)

294 (91.6)

0.009

 Years of age

55 (44.8–61.1)

57.8 (50–63)

54.3 (42–60)

0.001

 Years of formal education

9 (6–13.3)

9 (6–12)

10 (6–14)

0.004

 Medium-low SE level1

388 (93.5)

90 (95.7)

298 (92.8)

0.475

RA-related

 Serum positive RF1

373 (89.9)

83 (88.3)

290 (90.3)

0.562

 Serum positive ACCP1

373 (89.9)

82 (87.2)

291 (90.7)

0.334

 Years of disease duration

13.3 (8–18.6)

16.6 (12–20)

12.5 (7–18)

≤ 0.0001

 Rheumatoid nodes1

95 (22.9)

49 (63.9)

46 (13.6)

≤ 0.0001

 RAPID-3 score

4.7 (1.7–11.8)

13 (4–17)

3.2 (1.4–9)

≤ 0.0001

 High disease activity category1

96 (23.1)

48 (51.1)

48 (15)

≤ 0.0001

Patient-reported outcomes

 Pain-VAS

5 (2–17.3)

14 (5.6–39)

4 (1–10)

≤ 0.0001

 Overall disease-VAS

5.3 (1–20)

16 (5–39)

4 (1–16)

≤ 0.0001

 HAQ score

0.25 (0–1.13)

1.13 (0.13–2)

0.13 (0–1)

≤ 0.0001

 SF-36 score

71.9 (51.2–86.1)

54 (42–78.7)

75.5 (58–88)

≤ 0.0001

 Mental component score (SF-36)

75 (54.6–88.2)

57 (46.8–81)

78 (59.4–90)

≤ 0.0001

 Physical component score (SF-36)

68.9 (48.9–86.3)

47.8 (39–76)

75 (54–88.4)

≤ 0.0001

Comorbidity

 Presence of comorbidity1

255 (61.4)

72 (76.6)

183 (75)

0.001

 Surgical joint replacement1

87 (21)

58 (61.7)

29 (9)

≤ 0.0001

Treatment

 DMARDs/patient

1 (1–2)

2 (1–2)

1 (1–2)

0.008

 Corticosteroids use1

182 (43.9)

38 (40.4)

144 (44.9)

0.480

 Intensive treatment1

66 (15.9)

19 (20.2)

47 (14.6)

0.202

Compliance with treatment

 Adherence1

227 (54.7)

46 (48.9)

182 (56.7)

0.196

 Persistence1

228 (54.9)

41 (43.6)

186 (57.9)

0.018

 Concordance1

183 (44.1)

33 (35.1)

150 (46.7)

0.058

Miscellaneous

 Health Literacy1

329 (79.3)

80 (85.1)

249 (77.6)

0.147

 Adequate RA knowledge1 (based on CQ)

195 (47)

31 (33)

164 (51)

0.002

 RA family history1

186 (44.8)

58 (61.7)

128 (39.9)

≤ 0.0001

  1. Data are presented as the median (IQR) unless otherwise indicated
  2. 1Number (%) of patients
  3. SE socioeconomic, RF rheumatoid factor, ACCP antibodies to cyclic citrullinated peptides, RAPID-3 Routine Assessment of Patients Index Data-3 score, VAS visual analogue scale, HAQ Health Assessment Questionnaire, SF-36 Short Form-36, DMARDs disease-modifying anti-rheumatic drugs, CQ Compliance Questionnaire, RA rheumatoid arthritis