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Table 1 Population characteristics and their comparison among patients with and without significant RP

From: Markers of disease severity and positive family history are associated to significant risk perception in rheumatoid arthritis, while compliance with therapy is not: a cross-sectional study in 415 Mexican outpatients

Characteristics Entire population, N = 415 Patients with significant RP, N = 94 Patients without significant RP, N = 321 p
Socio-demographic
 Female sex1 387 (93.3) 93 (98.9) 294 (91.6) 0.009
 Years of age 55 (44.8–61.1) 57.8 (50–63) 54.3 (42–60) 0.001
 Years of formal education 9 (6–13.3) 9 (6–12) 10 (6–14) 0.004
 Medium-low SE level1 388 (93.5) 90 (95.7) 298 (92.8) 0.475
RA-related
 Serum positive RF1 373 (89.9) 83 (88.3) 290 (90.3) 0.562
 Serum positive ACCP1 373 (89.9) 82 (87.2) 291 (90.7) 0.334
 Years of disease duration 13.3 (8–18.6) 16.6 (12–20) 12.5 (7–18) ≤ 0.0001
 Rheumatoid nodes1 95 (22.9) 49 (63.9) 46 (13.6) ≤ 0.0001
 RAPID-3 score 4.7 (1.7–11.8) 13 (4–17) 3.2 (1.4–9) ≤ 0.0001
 High disease activity category1 96 (23.1) 48 (51.1) 48 (15) ≤ 0.0001
Patient-reported outcomes
 Pain-VAS 5 (2–17.3) 14 (5.6–39) 4 (1–10) ≤ 0.0001
 Overall disease-VAS 5.3 (1–20) 16 (5–39) 4 (1–16) ≤ 0.0001
 HAQ score 0.25 (0–1.13) 1.13 (0.13–2) 0.13 (0–1) ≤ 0.0001
 SF-36 score 71.9 (51.2–86.1) 54 (42–78.7) 75.5 (58–88) ≤ 0.0001
 Mental component score (SF-36) 75 (54.6–88.2) 57 (46.8–81) 78 (59.4–90) ≤ 0.0001
 Physical component score (SF-36) 68.9 (48.9–86.3) 47.8 (39–76) 75 (54–88.4) ≤ 0.0001
Comorbidity
 Presence of comorbidity1 255 (61.4) 72 (76.6) 183 (75) 0.001
 Surgical joint replacement1 87 (21) 58 (61.7) 29 (9) ≤ 0.0001
Treatment
 DMARDs/patient 1 (1–2) 2 (1–2) 1 (1–2) 0.008
 Corticosteroids use1 182 (43.9) 38 (40.4) 144 (44.9) 0.480
 Intensive treatment1 66 (15.9) 19 (20.2) 47 (14.6) 0.202
Compliance with treatment
 Adherence1 227 (54.7) 46 (48.9) 182 (56.7) 0.196
 Persistence1 228 (54.9) 41 (43.6) 186 (57.9) 0.018
 Concordance1 183 (44.1) 33 (35.1) 150 (46.7) 0.058
Miscellaneous
 Health Literacy1 329 (79.3) 80 (85.1) 249 (77.6) 0.147
 Adequate RA knowledge1 (based on CQ) 195 (47) 31 (33) 164 (51) 0.002
 RA family history1 186 (44.8) 58 (61.7) 128 (39.9) ≤ 0.0001
  1. Data are presented as the median (IQR) unless otherwise indicated
  2. 1Number (%) of patients
  3. SE socioeconomic, RF rheumatoid factor, ACCP antibodies to cyclic citrullinated peptides, RAPID-3 Routine Assessment of Patients Index Data-3 score, VAS visual analogue scale, HAQ Health Assessment Questionnaire, SF-36 Short Form-36, DMARDs disease-modifying anti-rheumatic drugs, CQ Compliance Questionnaire, RA rheumatoid arthritis