Markers of disease severity and positive family history are associated to significant risk perception in rheumatoid arthritis, while compliance with therapy is not: a cross-sectional study in 415 Mexican outpatients

Contreras-Yáñez, Irazú; Lavielle, Pilar; Clark, Patricia; Pascual-Ramos, Virginia

doi:10.1186/s13075-021-02440-y

Table 3 Comparison of the characteristics from unrealistic pessimistic RP patients and unrealistic optimistic RP patients

From: Markers of disease severity and positive family history are associated to significant risk perception in rheumatoid arthritis, while compliance with therapy is not: a cross-sectional study in 415 Mexican outpatients

Characteristics	Unrealistic pessimistic RP patients, N = 32	Unrealistic optimistic RP patients, N = 24	p
Socio-demographic
Female sex¹	31 (96.9)	24 (100)	1
Years of age	59.5 (49.6–64.6)	57.1 (43.3–61.7)	0.329
Years of formal education	9 (6–15.8)	9 (6–12)	0.590
Medium-low SE level¹	29 (90.6)	24 (100)	0.252
RA-related
Serum positive RF¹	24 (75)	24 (100)	0.008
Serum positive ACCP¹	25 (78.1)	24 (100)	0.016
Years of disease duration	13.5 (8.7–18)	18.5 (7.4–25)	0.329
Rheumatoid nodes¹	15 (46.9)	13 (54.2)	0.787
RAPID-3	4.1 (1.4–12.6)	15.3 (14.1–18.7)	0.002
High disease activity category¹	6 (18.8)	19 (79.2)	≤ 0.0001
Patient-reported outcomes
Pain-VAS	8 (3.3–14)	27.5 (7.6–36)	0.007
Overall disease-VAS	7.5 (2–15)	32.5 (7.5–45.8)	0.001
HAQ score	0.25 (0–1.1)	2 (1.4–2.5)	≤ 0.0001
SF-36 score	77.2 (55.4–87.3)	42.5 (22.6–67)	≤ 0.0001
Mental component score (SF-36)	71.9 (56.5–87.8)	48.1 (32–67)	0.002
Physical component score (SF-36)	74 (48.9–84.6)	39.7 (17.4–53.3)	≤ 0.0001
Comorbidity
Presence of comorbidity¹	19 (59.4)	19 (79.2)	0.153
Surgical joint replacement¹	9 (28.1)	13 (54.2)	0.059
Treatment
DMARDs/patient	1 (1–2)	2 (1–2)	0.165
Corticosteroids use¹	11 (34.4)	18 (75)	0.003
Intensive treatment¹	10 (31.3)	18 (75)	0.003
Compliance with treatment
Adherence¹	18 (56.3)	11 (45.8)	0.590
Persistence¹	19 (59.4)	111 (45.8)	0.418
Concordance¹	15 (46.9)	10 (41.7)	0.789
Miscellaneous
Health Literacy¹	24 (75)	22 (91.7)	0.162
Adequate RA knowledge¹ (based on CQ)	25 (44.6)	170 (47.4)	0.774
RA family history¹	18 (56.3)	10 (41.7)	0.418
Significant RP¹	32 (100)	0	≤ 0.0001
Unfavorable medical criteria	5 (5–6)	7.5 (7–8)	≤ 0.0001

Data are presented as the median and IQR unless otherwise indicated
¹Number (%) of patients
SE socioeconomic, RF rheumatoid factor, ACCP antibodies to cyclic citrullinated peptides, RAPID-3 Routine Assessment of Patients Index Score-3, VAS visual analogue scale, HAQ Health Assessment Questionnaire, SF-36 Short Form-36, DMARDs disease-modifying anti-rheumatic drugs, CQ Compliance Questionnaire, RA rheumatoid arthritis, RP risk perception

Back to article page