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Table 4 Comparison of unrealistic and realistic RP patients’ characteristics

From: Markers of disease severity and positive family history are associated to significant risk perception in rheumatoid arthritis, while compliance with therapy is not: a cross-sectional study in 415 Mexican outpatients

Characteristics

Unrealistic patients, N = 56

Realistic patients, N = 359

p

Socio-demographic

 Female sex1

55 (98.2)

332 (92.5)

0.152

 Years of age

58.5 (46.4–63)

54.7 (44.8–60.7)

0.082

 Years of formal education

9 (6–14.8)

9 (6–13)

0.372

 Medium-low SE level1

53 (94.6)

335 (93.3)

1

RA-related

 Serum positive RF1

48 (85.7)

325 (90.5)

0.337

 Serum positive ACCP1

49 (87.5)

324 (90.3)

0.481

 Years of disease duration

14 (8.3–20.3)

13.2 (7.7–18.3)

0.224

 Rheumatoid nodes1

28 (50)

67 (18.7)

≤ 0.0001

 RAPID-3

10.8 (2–18)

4.2 (1.6–10)

0.004

 High disease activity category1

25 (44.6)

71 (19.8)

≤ 0.0001

Patient-reported outcomes

 Pain-VAS

9.8 (5–31)

5 (2–16)

≤ 0.0001

 Overall disease-VAS

10 (5–35)

5 (1–18)

0.001

 HAQ score

1 (0–2.1)

0.25 (0–1.1)

0.001

 SF-36 score

61.3 (41.1–81.1)

73 (54.3–87)

0.002

 Mental component score (SF-36)

62.5 (42.9–86.9)

76.6 (56.9–88.4)

0.008

 Physical component score (SF-36)

55.3 (38–80)

70.4 (51.4–87.8)

0.003

Comorbidity

 Presence of comorbidity1

38 (67.9)

217 (60.4)

0.306

 Surgical joint replacement1

22 (39.3)

65 (18.1)

0.001

Treatment

 DMARDs/patient

1 (1–2)

1 (1–2)

0.031

 Corticosteroids use1

29 (51.8)

153 (42.6)

0.247

 Intensive treatment1

28 (50)

144 (40.1)

0.190

Compliance with treatment

 Adherence1

29 (51.8)

199 (55.4)

0.666

 Persistence1

30 (53.6)

197 (54.9)

0.886

 Concordance1

25 (44.6)

158 (44)

1

Miscellaneous

 Health Literacy1

46 (82.1)

283 (78.8)

0.723

 Adequate RA knowledge1 (based on CQ)

25 (44.6)

170 (47.4)

0.774

 RA family history1

28 (50)

158 (44)

0.470

Significant RP1

32 (57.1)

62 (17.3)

≤ 0.0001

Unfavorable medical criteria

6 (5–7)

5 (4–6)

≤ 0.0001

  1. Data are presented as the median and IQR unless otherwise indicated
  2. 1Number (%) of patients
  3. SE socioeconomic, RF rheumatoid factor, ACCP antibodies to cyclic citrullinated peptides, RAPID-3 Routine Assessment of Patients Index Score-3, VAS visual analogue scale, HAQ Health Assessment Questionnaire, SF-36 Short Form-36, DMARDs disease-modifying anti-rheumatic drugs, CQ Compliance Questionnaire, RA rheumatoid arthritis, RP risk perception