Fig. 1
From: Elucidating the cellular mechanism for E2-induced dermal fibrosis
E2-induced TGFβ1 and TGFβ2 transcription in vitro. Steady-state mRNA levels 24 h post vehicle vs. E2 stimulation in vitro. Steady-state mRNA levels of TGFβ1 (a) and TGFβ2 (b). Normalized to B2M. Data shown are from 8 independent experiments using dermal fibroblasts from 8 different donors. Bars = mean ± SEM. Statistical test: Two-tailed, Wilcoxon matched-pairs signed rank test.*p ≤ 0.05