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Table 3 Genotype frequencies of rs755622 and -794 CATT5-8 polymorphisms in control and OA groups

From: Macrophage migration inhibitory factor may play a protective role in osteoarthritis

Genotype Control OA Hip OA Knee OA
  n = 113
(%)
n = 119
(%)
p value* n = 64
(%)
p value* n = 55
(%)
p value*
rs755622    0.19   0.24   0.31
GG 90 (79.6) 86 (72.3)   46 (71.9)   40 (72.7)  
GC 20 (17.7) 31 (26.1)   17 (26.6)   14 (25.5)  
CC 3 (2.7) 2 (1.7)   1 (1.6)   1 (1.8)  
-794 CATT5-8    0.83   0.38   0.55
6/6 8 (7.1) 10 (8.4)   4 (6.3)   6 (10.9)  
6/7 41 (36.3) 35 (29.4)   16 (25)   19 (34.5)  
6/8 1 (0.9) 6 (5.0)   4 (6.3)   2 (3.6)  
7/7 48 (42.5) 47 (39.5)   30 (46.9)   17 (30.9)  
7/8 13 (11.5) 21 (17.6)   10 (15.6)   11 (20)  
8/8 2 (1.8) 0 (0)   0 (0)   0 (0)  
  1. MIF macrophage migration inhibitory factor, OA osteoarthritis
  2. *P values for rs755622 were obtained by chi-squared test of the distribution of genotypes containing C allele (GG vs. GC + CC); p values for -794 CATT5-8 were obtained by chi-squared test of the distribution of genotypes containing 7 or above CATT-repeats in both alleles (6/6+6/7+6/8 vs. 7/7+7/8+8/8)