Table 3 Synthesis of main outcomes of the effect of bisphosphonates

Alendronate (n = 11)

Adebayo et al. [38]

?

+

x

?

x

Khorasani et al. [39]

?

?

x

–

+

Zhu et al. [31]

?

+

x

x

+

Mohan et al. [32]

?

+

x

x

?

Panahafir et al. [33]

+

x

x

+

x

Shirai et al., 2011 [23]

+

+

x

–

+

Zhang et al. [24]

+

+

x

x

+

Sniekers et al. [40]

+

+

x

x

x

Jones et al. [35]

+

+

x

+

x

Ding et al. [42]

–

+

x

x

x

Hayami et al. [37]

+

+

x

+

+

Zoledronic acid (n = 7)

She et al. [20]

+

+

x

x

x

Cinar et al. [29]

+

x

+

x

–

Bagi et al. [30]

–

+

x

–

+

Lampropoulou et al. [21]

+

x

x

x

x

Dearmin et al., 2014 [43]

+

x

x

–

+

Strassle et al. [36]

+

+

?

x

x

Muehleman et al., 2002 [28]

+

x

x

x

+

Risedronate (n = 6)

Permuy et al. [22]

+

+

+

x

x

Thomsen et al. [41]

–

?

x

x

+

Jones et al. [35]

+

+

x

–

x

MacNeil et al. [25]

+

+

x

–

x

Doschak et al. [26]

–

+

x

x

x

Doschak et al. [27]

–

+

x

–

x

Tiludronate (n = 2)

Moreau et al. [45]

–

+

+

–

+

Pelletier et al. [44]

+

x

x

x

+

Pamidronate (n = 1)

Koh et al. [34]

+

+

x

x

x