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Table 1 Demographics of patients in 2004, 2009 and 2015

From: Comprehensive assessment of alterations in hand deformities over 11 years in patients with rheumatoid arthritis using cluster analysis and analysis of covariance

   2004 2009 2015 p value
age (year) 62.2 66.3 70.1 N/A
affected time (year) 18.1 23.1 28.5 N/A
CRP (mg/dl) 1.31 0.97 0.79 0.275
ESR (mm/hr) 52.1 27.9* 34.7** 0.001
MMP-3 (ng/dl) 179.5 149.1 171.5 0.743
DAS28   no data 3.17 3 0.32
  1. Numbers show the averages at each endpoint. Analysis of variance with post hoc Bonferroni test was used for multiple comparison
  2. CRP C-reactive protein, ESR erythrocyte sedimentation rate, MMP matrix metalloprotease, DAS disease activity score
  3. *: p = 0.001, *: p = 0.019