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Table 4 Breast cancer risk as a function of number of SLE autoantibodies, compared to the general population

From: Association of systemic lupus erythematosus autoantibody diversity with breast cancer protection

Number of autoantibodies

N

No. obs.

No. exp.

SLE cohort SIR (95%CI)

p value

AA* SIR (95%CI)

AA p value

Non-AA^ SIR (95%CI)

Non-AA p value

0–2 antibodies

1301

15

17.8

0.84 (0.47–1.39)

0.60

1.72 (0.86–3.08)

0.12

0.35 (0.10–0.90)

0.023

3+ antibodies

1130

7

17.1

0.41 (0.16–0.84)

0.010

0.65 (0.21–1.51)

0.43

0.21 (0.03–0.77)

0.010

  1. N sample size, AA African American, non-AA non-African American
  2. *N = 966 SLE patients contributing 8488 person-years
  3. ^N = 1465 SLE patients contributing 11,911 person-years