Table 1 Arsenic trioxide safety at week 24

Total number of ATO-related AEs

22

Treatment-emergent SAEs

4

Neutropenia*

2

Axonal neuropathy†

1

Osteitis‡

1

 Neutropenia grade 3

2

Treatment-related AEs (mild to moderate)

18

 Anaemia (grade 2)

2

 Diarrhoea (grade 1)

5

 Nausea

2

 Hypomagnesaemia

1

 Mild QT prolongation (grade 1)

2

 Injection-related reaction

1

 Injection site reaction

1

 Hypotension

1

 Flushing

1

 Increased transaminases (grade 1)

1

 Fatigue

1