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Table 2 Confusion factors and FDG PET/CT scan findings in controls (n = 89) and in SSc patients (n = 36)

From: 18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study

  Controls (n = 89) SSc patients (n = 36) p value
Potential confusion factors
 Sex, female, no. (%) 47 (52.8) 20 (55.6) 0.78
 Age, years, mean ± SD 61.7 ± 12.8 57.9 ± 13.0 0.23
 BMI, kg/m2, mean ± SD 25.9 ± 5.1 25.3 ± 5.9 0.59
 Glycemia, g/L, mean ± SD 1.0 ± 0.3 1.0 ± 0.2 0.42
 Injection-perfusion duration, minutes, mean ± SD 73.5 ± 12.3 73.5 ± 12.0 1.0
18F-FDG PET/CT scan findings, no. (%)
 Lung
  Abnormal interstitial lung pattern 1 (1.1) 15 (41.7) <.001
  hv/SUVmax, mean ± SD 1.5 ± 0.3 2.1 ± 1.0 <.001
  S/SUVmax, mean ± SD 11.1 ± 2.2 14.4 ± 6.4 0.005
  S/Intensities, median (IQR) 0.0 (0.0; 0.0) 2.5 (0.0; 10.0) <.001
 Lymph node
  Mediastinal, abnormal pattern 0 (0.0) 9 (25.0) <.001
  Hilar, abnormal pattern 2 (2.2) 8 (22.2) <.001
 Osteoarticular, abnormal pattern 2 (2.2) 1 (2.8) NA
 Muscles, abnormal pattern 2 (2.2) 3 (8.3) NA
 Skin, abnormal pattern 2 (2.2) 2 (5.6) NA
 Esophagus, abnormal pattern 81 (91.0) 26 (72.2) 0.007
 Calcinosis, abnormal pattern 0 (0.0) 0 (0.0) NA
  1. BMI body mass index, hv/SUVmax highest value of SUVmax among the 10 pulmonary SUVmax, IQR interquartile range, NA non-applicable, SD standard deviation, S/Intensities sum of the 10 pulmonary intensities, S/SUVmax sum of the 10 pulmonary SUVmax, SSc systemic sclerosis. p value adjusted on BMI, <.001