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Table 2 Confusion factors and FDG PET/CT scan findings in controls (n = 89) and in SSc patients (n = 36)

From: 18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study

 

Controls (n = 89)

SSc patients (n = 36)

p value

Potential confusion factors

 Sex, female, no. (%)

47 (52.8)

20 (55.6)

0.78

 Age, years, mean ± SD

61.7 ± 12.8

57.9 ± 13.0

0.23

 BMI, kg/m2, mean ± SD

25.9 ± 5.1

25.3 ± 5.9

0.59

 Glycemia, g/L, mean ± SD

1.0 ± 0.3

1.0 ± 0.2

0.42

 Injection-perfusion duration, minutes, mean ± SD

73.5 ± 12.3

73.5 ± 12.0

1.0

18F-FDG PET/CT scan findings, no. (%)

 Lung

  Abnormal interstitial lung pattern

1 (1.1)

15 (41.7)

<.001

  hv/SUVmax, mean ± SD

1.5 ± 0.3

2.1 ± 1.0

<.001

  S/SUVmax, mean ± SD

11.1 ± 2.2

14.4 ± 6.4

0.005

  S/Intensities, median (IQR)

0.0 (0.0; 0.0)

2.5 (0.0; 10.0)

<.001

 Lymph node

  Mediastinal, abnormal pattern

0 (0.0)

9 (25.0)

<.001

  Hilar, abnormal pattern

2 (2.2)

8 (22.2)

<.001

 Osteoarticular, abnormal pattern

2 (2.2)

1 (2.8)

NA

 Muscles, abnormal pattern

2 (2.2)

3 (8.3)

NA

 Skin, abnormal pattern

2 (2.2)

2 (5.6)

NA

 Esophagus, abnormal pattern

81 (91.0)

26 (72.2)

0.007

 Calcinosis, abnormal pattern

0 (0.0)

0 (0.0)

NA

  1. BMI body mass index, hv/SUVmax highest value of SUVmax among the 10 pulmonary SUVmax, IQR interquartile range, NA non-applicable, SD standard deviation, S/Intensities sum of the 10 pulmonary intensities, S/SUVmax sum of the 10 pulmonary SUVmax, SSc systemic sclerosis. p value adjusted on BMI, <.001