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Table 3 Population attributable fractions (PAF) for population counterfactuals of incident gout among weight change patterns across adulthood

From: Incident gout and weight change patterns: a retrospective cohort study of US adults

Scenario† PAF (%), 95% CI total population PAF (%), 95% CI subpopulation#
1. From gaining to stable non-obese 11.5 (4.6–17.9) 36.4 (18.6–50.3)
2. From stable obese to stable non-obese 3.2 (0–6.3) 37.6 (6.0–58.7)
3. Total population to stable normal 32.9 (18.2–44.9) 42.8 (25.8–55.9)
  1. Source: NHANES (2007–2014)
  2. †Adjusted for ethnicity, sex, age, current smoke (yes/no), annual household income, diabetes, hypertension, and alcohol consumption
  3. From a younger age to an older age: scenario 1, if those who gained weight, instead remained non-obese; scenario 2, if those who maintained an obese BMI, instead lost to a non-obese BMI; scenario 3, if the total population had a normal BMI from young adulthood that was maintained through midlife
  4. #Scenario 1: subpopulation represents the gaining group; scenario 2: subpopulation represents the stable obese group; scenario 3: subpopulation represents the population whose BMI ≥ 25 kg/m2
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Arthritis Research & Therapy

ISSN: 1478-6362

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