Serum chitinase-3-like 1 protein is a useful biomarker to assess disease activity in ANCA-associated vasculitis: an observational study

Table 2 Linear regression analyses of laboratory variables for the current BVAS and FFS

	Univariate analysis			Multivariate analysis
	Regression coefficient (crude B)	Correlation coefficient (R = β)	p-value	Standardised β	p-value
Laboratory variables vs. BVAS
White blood cell count	0.001	0.271	0.037
Neutrophil count	0.001	0.393	0.002
Platelet count	0.013	0.192	0.141
ESR	0.073	0.350	0.006
CRP	0.113	0.446	< 0.001	0.371	0.002
Creatinine	0.870	0.246	0.058
AST	− 0.025	− 0.054	0.681
ALT	0.097	0.199	0.128
Serum YKL-40	0.026	0.393	0.002	0.301	0.012
Laboratory variables vs. FFS
White blood cell count	0.000	0.043	0.745
Neutrophil count	0.000	0.114	0.385
Platelet count	− 0.001	− 0.109	0.406
ESR	0.006	0.195	0.136
CRP	0.010	0.270	0.037
Creatinine	0.284	0.567	< 0.001	0.329	0.004
AST	0.014	0.213	0.102
ALT	0.018	0.263	0.043
Serum YKL-40	0.006	0.641	< 0.001	0.476	< 0.001

BVAS Birmingham vasculitis activity score, FFS Five factor score, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, AST aspartate aminotransferase, ALT alanine aminotransferase

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