|
Age, years (mean [SD])a
|
53.1 (7.28)
|
54.8 (10.72)
|
|
Sex, n (%)
|
|
Female
|
15 (83)
|
27 (82)
|
|
Male
|
3 (17)
|
6 (18)
|
|
BMI, kg/m2 (mean [SD])
|
26.5 (4.35)
|
27.8 (4.48)
|
|
Ethnicity, n (%)
|
|
Hispanic or Latino
|
0
|
2 (6)
|
|
Not Hispanic or Latino
|
18 (100)
|
31 (94)
|
|
Race detail
|
|
American Indian or Alaskan native
|
0
|
1 (3)
|
|
White—White/Caucasian/European Heritage
|
18 (100)
|
32 (97)
|
|
Time since formal diagnosis of RA, years
|
|
Mean (SD)
|
4.5 (3.27)
|
7.3 (7.24)
|
|
Median (min, max)
|
3.9 (0.6, 12.9)
|
4.4 (0.4, 31.1)
|
|
Time since onset of first musculoskeletal symptoms, years
|
|
Mean (SD)
|
6.6 (4.30)
|
9.5 (8.44)
|
|
Median (min, max)
|
5.5 (2.1, 14.4)
|
7.8 (0.6, 33.1)
|
|
Baseline medical conditions, n (%)
|
|
Cardiovascular risk factors
|
8 (44)
|
12 (36)
|
|
Other risk factors
|
11 (61)
|
19 (58)
|
|
Baseline (day 1) DAS28-CRP
|
|
Mean (SD)
|
5.4 (1.17)
|
5.2 (0.76)
|
|
Median (min, max)a
|
5.5 (1.9, 7.2)
|
5.1 (3.7, 7.1)
|
|
Baseline (day 1) CRP
|
|
Mean (SD)
|
19.8 (15.52)
|
14.4 (19.47)
|
|
Median (min, max)a
|
15.1 (1.3, 53.5)
|
9.4 (0.9, 98.2)
|
|
Baseline (day 1) RAMRIS
|
|
Synovitis
|
|
Mean (SD)
|
6.4 (4.70)
|
10.5 (4.97)
|
|
Median (min, max)
|
6.0 (0, 15)
|
10.0 (2, 20)
|
|
Bone erosion
|
|
Mean (SD)
|
11.5 (11.02)
|
16.5 (13.36)
|
|
Median (min, max)
|
7.0 (1, 40)
|
16.0 (1, 54)
|
|
Osteitis
|
|
Mean (SD)
|
5.3 (7.97)
|
6.4 (9.61)
|
|
Median (min, max)
|
1.0 (0, 28)
|
2.0 (0, 36)
|
|
Baseline (day 1) CARLOS
|
|
Mean (SD)
|
4.7 (9.32)
|
6.0 (9.06)
|
|
Median (min, max)
|
0 (0, 34)
|
1.5 (0, 36)
|
|
Baseline (day 1) Vectra DA
|
|
Mean (SD)
|
50.8 (14.85)
|
50.9 (13.39)
|
|
Median (min, max)
|
51.5 (21, 69)
|
49.0 (29, 89)
|
|
Baseline (day 1) HAQ-DI
|
|
Mean (SD)
|
1.3 (0.79)
|
1.2 (0.61)
|
|
Median (min, max)
|
1.6 (0.0, 2.3)
|
1.4 (0.0, 2.1)
|
|
Baseline (day 1) FACIT-Fatigue
|
|
Mean (SD)
|
24.3 (9.92)
|
32.6 (10.18)
|
|
Median (min, max)
|
23.5 (8, 50)
|
32.5 (16, 52)
|
