Table 3 Change from baseline in DAS28-CRP scores at day 85 (MMRM analysis)
Treatment regimen | N (n) | LS mean (SE) | 95% CI for LS mean | Difference from placebo | 95% CI for differences |
|---|---|---|---|---|---|
Change from baseline at day 85 | |||||
 Placebo (b.i.d. and t.i.d.) | 18 (15) | −0.90 (0.31) | (−1.51, −0.28) |  |  |
 GSK2982772 (b.i.d. and t.i.d.) | 33 (27) | −1.27 (0.23) | (−1.73, −0.81) | −0.38 | (−1.15, 0.40) |
Change from baseline at day 85 by treatment regimen | |||||
 Placebo (b.i.d.) | 3 (3) | −1.00 (0.72) | (−2.45, 0.46) |  |  |
 GSK2982772 (b.i.d.) | 5 (5) | −1.47 (0.56) | (−2.60, −0.35) | − 0.48 | (−2.33, 1.37) |
 Placebo (t.i.d.) | 15 (12) | −0.87 (0.35) | (−1.57, − 0.17) |  |  |
 GSK2982772 (t.i.d.) | 28 (22) | −1.23 (0.26) | (−1.75, −0.71) | −0.36 | (− 1.23, 0.52) |