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Table 1 Clinical characteristics of patients with gout or osteoarthritis

From: Neutrophil extracellular trap clearance by synovial macrophages in gout

 

Gout

(n = 25)

OA

(n = 10)

P

Age (years, median [IQR])

63 (50–78)

62 (56–66)

0.694

Male (%)

25 (100%)

4 (40.0%)

<  0.001

CRP (mg/dL, median [IQR])

12.08 (4.44–17.75)

0.22 (0.10–1.00)

<  0.001

Uric acid (mg/dL, median [IQR])

6.0 (5.1–9.3)

5.0 (4.1–6.7)

0.137

Involved joint

 Knee

24 (96.0%)

10 (100%)

1.000

 Ankle

8 (32.0%)

1 (10.0%)

0.234

 Foot

5 (20.0%)

0 (0%)

0.291

Treatment

 IA steroid

19 (76.0%)

3 (30.0%)

0.019

 Systemic steroid

11 (44.0%)

1 (10.0%)

0.112

 NSAIDs

9 (36.0%)

7 (70.0%)

0.131

Urate-lowering therapy

 Allopurinol

2 (8.0%)

0 (0%)

0.579

 Febuxostat

6 (24.0%)

0 (0%)

0.151

Joint fluid analysis

 WBCs (/μL, median [IQR])

33,500 (20750–53,955)

150 (74–554)

<  0.001

 Neutrophil (/μL, median [IQR])

28,800 (18184–49,206)

2 (0–19)

<  0.001

  1. CRP C-reactive protein, IA intraarticular, WBCs white blood cells