Skip to main content

Table 5 The AUC, sensitivity, specificity, and likelihood ratio of PET/CT parameters, serologic markers, and systemic scoring for predicting the occurrence of MAS

From: Total metabolic lesion volume of lymph nodes measured by 18F-FDG PET/CT: a new predictor of macrophage activation syndrome in adult-onset Still’s disease

Factor AUC (95% CI) Cutoff value Sensitivity, % (95% CI) Specificity, % (95% CI) Likelihood ratio
IL-2R 0.899 (0.776–0.999) 2824 pg/ml 75.0 (40.9–95.6) 97.3 (48.7–99.9) 27.8
MLVtotal of LNs 0.855 (0.642–0.999) 62.2 80.0 (37.6–99.0) 93.9 (80.4–98.9) 13.2
SUVmax of the spleen 0.765 (0.630–0.900) 3.55 100.0 (67.6–100.0) 53.1 (39.4–66.3) 2.13
Systemic score ≥ 7 0.713 (0.541–0.885)   87.5 (52.9–99.4) 55.1 (41.3–68.1) 1.95
Ferritin > 5 ULN 0.642 (0.455–0.828)   87.5 (52.9–99.4) 40.8 (28.2–54.8) 1.48
  1. LN lymph node, MLV metabolic lesion volume, IL-2R interleukin-2 receptor, MAS macrophage activation syndrome. MLVtotal of LNs were calculated from the patients with hypermetabolic lymph nodes (n = 38)