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Table 2 Prevalence of CPFE in patients with SSc or SSc-ILD

From: Effect of combined pulmonary fibrosis and emphysema on patients with connective tissue diseases and systemic sclerosis: a systematic review and meta-analysis

Study

Number of studied patients (n)

Prevalence (%, n)

SSc

SSc-ILD with or without emphysema

SSc-CPFE

CPFE in patients with SSc

SSc-CFPE in SSc-ILD with or without emphysema

SSc-CPFE in smokers

SSc-CPFE in non-smokers

Antoniou et al./2016 [3]

333

41

12.3

19.7 (26/132)

7.5 (15/201)

Ariani et al./2019 [4]

239

43

18.0

14.7 (16/109)

7.1 (25/351)

Champtiaux et al./2018 [5]

276

131*

10

3.6

7.6

Pooled data

 

703

94

 

13.4

17.4

5.3

  1. SSc systemic sclerosis, SSc-ILD the patients with systemic sclerosis and interstitial lung disease, CPFE combined pulmonary fibrosis and emphysema, CTD-CPFE connective tissue disease and combined pulmonary fibrosis and emphysema, CTD-ILD connective tissue disease and interstitial lung disease
  2. *Number of patients with confirmed ILD in patients with SSc