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Table 3 Genetically predicted age at menarche, age at menopause, and age at first birth with the risk of rheumatoid arthritis. Multivariable analysis adjusting for the effect of body mass index and year of education

From: Age at menarche, age at natural menopause, and risk of rheumatoid arthritis — a Mendelian randomization study

Methods

#SNP

OR (95% CI)

P-value

Age at menarche

 Body mass index

140

0.97 (0.83–1.13)

0.12

 Year of education

316

1.07 (0.98–1.16)

0.11

Age at natural menopause

 Body mass index

51

1.06 (0.99–1.27)

0.08

 Year of education

54

1.04 (0.98–1.11)

0.18

Age at first birth

 Body mass index

10

0.85 (0.57–1.24)

0.40

 Year of education

10

1.10 (0.58–2.11)

0.76