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Table 1 Demographic features of cases and non-cases of gout

From: Risk of gout among Taiwanese adults with ALDH-2 rs671 polymorphism according to BMI and alcohol intake

Variables

No gout (n = 6901)

Gout (n = 2352)

p-value

Categorical variables

n (%)

n (%)

 

 ALDH2 rs671 genotype

  GG

3423 (49.60)

1237 (52.59)

0.0122

  GA+AA

3478 (50.40)

1115 (47.41)

 Alcohol drinking

  No

6345 (91.94)

1966 (83.59)

< 0.0001

  Yes

556 (8.06)

386 (16.41)

 Body mass index

  Normal (≥ 18.5 to <24Kg/m2)

3790 (54.92)

665 (28.27)

< 0.0001

  Abnormal (< 18.5 and ≥ 24 Kg/m2)

3111 (45.08)

1687 (71.73)

 Sex

  Women

4163 (60.32)

773 (32.87)

< 0.0001

  Men

2738 (39.68)

1579 (67.13)

 Age group (years)

  30–40

1803 (26.13)

612 (26.02)

0.0004

  41–50

2001 (29.00)

584 (24.83)

  51–60

1944 (28.17)

718 (30.53)

  61–70

1153 (16.71)

438 (18.62)

 Waist-hip ratio

  Normal (men < 0.9; women < 0.85)

4048 (58.66)

960 (40.82)

< 0.0001

  Abnormal (men ≥ 0.9; women ≥ 0.85)

2853 (41.34)

1392 (59.18)

 Body fat (%)

  Normal (men < 25; women < 30)

3953 (57.28)

987 (41.96)

< 0.0001

  Abnormal (men ≥ 25; women ≥ 30)

2948 (42.72)

1365 (58.04)

 Cigarette smoking status

  Never

5564 (80.63)

1607 (68.32)

< 0.0001

  Former

695 (10.07)

388 (16.50)

  Current

642 (9.30)

357 (15.18)

 Coffee consumption

  No

4613 (66.85)

1569 (66.71)

0.9036

  Yes

2288 (33.15)

783 (33.29)

 Tea consumption

  No

4506 (65.29)

1322 (56.21)

< 0.0001

  Yes

2395 (34.71)

1030 (43.79)

 Exercise

  No

3991 (57.83)

1370 (58.25)

0.7241

  Yes

2910 (42.17)

982 (41.75)

 Diet status

  Non-vegetarian

6208 (89.96)

2174 (92.43)

< 0.0001

  Former vegetarian

321 (4.65)

108 (4.59)

  Vegan

372 (5.39)

70 (2.98)

 Blood urea nitrogen (mg/dL)

  Normal (≤ 20)

6653 (96.41)

2187 (92.98)

< 0.0001

  Abnormal (> 20)

248 (3.59)

165 (7.02)

 

 Creatinine (mg/dL)

  Normal (men < 1.4; women < 1.2)

6885 (99.77)

2303 (97.92)

< 0.0001

  Abnormal (men ≥ 1.4; women ≥ 1.2)

16 (0.23)

49 (2.08)

Continuous variables

Mean ± SD

Mean ± SD

 

 HDL-C (mg/dL)

54.96 ± 13.19

47.42 ± 11.17

< 0.0001

 LDL-C (mg/dL)

118.70 ± 30.91

126.30 ± 32.91

< 0.0001

 Triglycerides (mg/dL)

103.60 ± 75.71

155.10 ± 123.10

< 0.0001

  1. n sample size, ALDH2 aldehyde dehydrogenase 2, SD standard deviation, HDL-C high-density lipoprotein cholesterol, LDC-C low-density lipoprotein cholesterol