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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Early detection of osteoarthritis in the rat with an antibody specific to type II collagen modified by reactive oxygen species

Fig. 1

Histological scoring of OA for the medial tibial plateau in the ACLT+pMx and DMM models. Rats underwent ACLT+pMx or DMM surgery and were sacrificed at various time points (N = 9–10 rats per time points). The ipsilateral or contralateral knees were taken for histological analysis. Slides were stained with toluidine blue and saffron du Gatinais and scored as detailed in the “Method”. Histological sections for the DMM model are shown with the region selected for scoring marked in red. The total histological score is shown for both models. Data on the graphs represent the total score for each animal (N = 9–10) and the mean for each time point and for the selected contralateral knees. Double asterisks and quadruple asterisks mean significantly different from contralateral with p < 0.01 or p < 0.0001, respectively

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Arthritis Research & Therapy

ISSN: 1478-6362

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