Skip to main content

Table 2 HRpQCT parameters among patients with and without RA

From: Bone mineral density and microarchitecture among Chinese patients with rheumatoid arthritis: a cross-sectional study with HRpQCT

Distal radius

RA group (n = 81)

Control group (n = 81)

Difference

P

Geometry

 

 Tt.Ar, mm2

280.8 ± 66.9

253.1 ± 51.5

10.9%

0.004

 Ct.Ar, mm2

57.5 ± 13.8

56.2 ± 11.1

2.3%

0.506

 Tb.Ar, mm2

227.2 ± 64.6

200.425 ± 48.5

13.4%

0.003

 Ct.Pm, mm2

71.0 ± 9.8

66.3 ± 7.5

7.1%

0.001

Volumetric BMD, mgHA/ccm

 Tt.vBMD

258.5 ± 83.2

284.3 ± 70.2

−9.1%

0.034

 Ct.vBMD

882.9 ± 111.6

911.7 ± 58.7

−3.2%

0.042

 Tb.vBMD

94.5 ± 42.7

106.6 ± 42.4

−11.4%

0.071

Microarchitecture

 BV/TV

0.144 ± 0.056

0.160 ± 0.057

−10.0%

0.073

 Tb.Th, mm

0.219 ± 0.019

0.219 ± 0.016

0.0%

0.864

 Tb.N, 1/mm

1.087 ± 0.326

1.148 ± 0.295

−5.3%

0.215

 Tb.Sp, mm

1.042 ± 0.538

0.931 ± 0.393

11.9%

0.136

 Tb.1/N.SD

0.360 (0.284–0.508)

0.318 (0.268–0.508)

13.2%

0.155

 Ct.Th, mm

0.978 ± 0.256

1.006 ± 0.188

−2.8%

0.431

 Ct.Po, %

0.60 (0.30–1.00)

0.50 (0.30–0.85)

20.0%

0.279

Distal tibia

RA group (n = 80)

Control group (n = 81)

Difference

P

Geometry

 Tt.Ar, mm2

712.4 ± 128.5

679.3 ± 110.4

4.9%

0.081

 Ct.Ar, mm2

101.9 ± 28.1

107.4 ± 21.8

−5.1%

0.164

 Tb.Ar, mm2

615.6 ± 124.3

577.2 ± 110.0

6.7%

0.039

 Ct.Pm, mm2

103.9 ± 9.5

101.3 ± 8.5

2.6%

0.071

Volumetric BMD, mgHA/ccm

 Tt.vBMD

218.1 ± 63.5

237.0 ± 51.8

−8.0%

0.040

 Ct.vBMD

859.8 ± 89.8

869.5 ± 77.4

−1.1%

0.465

 Tb.vBMD

109.3 ± 36.8

117.1 ± 36.5

−6.7%

0.179

Microarchitecture

 BV/TV

0.179 ± 0.047

0.189 ± 0.047

−5.3%

0.196

 Tb.Th, mm

0.241 ± 0.019

0.240 ± 0.019

0.4%

0.627

 Tb.N, 1/mm

1.116 ± 0.234

1.134 ± 0.207

−1.6%

0.608

 Tb.Sp, mm

0.939 ± 0.239

0.902 ± 0.194

4.1%

0.281

 Tb.1/N.SD

0.360 (0.284–0.508)

0.318 (0.268–0.508)

13.2%

0.398

 Ct.Th, mm

1.165 ± 0.307

1.255 ± 0.264

−7.2%

0.048

 Ct.Po, %

2.45 (1.40–3.95)

3.00 (1.45–3.90)

−16.7%

0.320

  1. HRpQCT measures at the radius and tibia among patients and healthy controls are presented, organized by geometric, volumetric, and microarchitectural parameters. Comparisons of each measure (mean ± SD) between patients with RA and health controls were calculated using the Student’s t test
  2. Tt.Ar total bone area, Ct.Ar cortical bone area, Tb.Ar trabecular bone area, Ct.Pm cortical perimeter, Tt.vBMD total volumetric BMD, Ct.vBMD cortical vBMD, Tb.vBMD trabecular vBMD, BV/TV trabecular bone volume fraction, Tb.Th trabecular thickness, Tb.N trabecular number, Tb.Sp trabecular separation, Tb.1/N.SD inhomogeneity of network, Ct.Th cortical thickness, Ct.Po intra-cortical porosity
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us