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Table 6 Multivariable linear regression analysis of factors associated with HRpQCT parameters at the distal tibia among patients with RA, n = 81

From: Bone mineral density and microarchitecture among Chinese patients with rheumatoid arthritis: a cross-sectional study with HRpQCT

Distal tibia

Tb.Ar (mm2)

Ct.Ar (mm2)

Tt.vBMD

Tb.vBMD

Ct.vBMD

Ct.Th (mm)

β

P

β

P

β

P

β

P

β

P

β

P

 

4.586

0.004

−1.059

0.000

−3.044

0.000

−0.823

0.083

−6.256

0.000

−0.012

0.002

Female

−112.593

0.009

−32.411

0.000

−30.981

0.064

−22.203

0.045

10.934

0.637

−0.288

0.001

BMI

−0.377

0.916

2.358

0.001

5.277

0.002

3.204

0.005

4.349

0.060

0.027

0.002

Grip strength

3.594

0.080

0.723

0.072

–

–

–

–

–

–

–

–

Duration, years

−0.367

0.806

−0.138

0.648

−1.351

0.077

−0.792

0.110

−0.232

0.829

−0.004

0.360

DAS28

11.27

0.202

3.131

0.097

−1.002

0.803

−1.041

0.692

−0.680

0.911

0.020

0.375

HAQ

–

–

−7.507

0.142

–

–

–

–

−11.368

0.525

−0.070

0.289

 

−17.152

0.543

–

–

28.834

0.046

–

–

9.501

0.625

0.106

0.140

Distal tibia

Tb.Th (μm)

Tb.N

Tb.Sp (mm)

Tb.1/N.SD

BV/TVBV/TV

Ct.Po (%)

β

P

β

P

β

P

β

P

β

P

β

P

Age, years

0.503

0.047

−0.006

0.057

0.007

0.042

0.003

0.164

0.000

0.473

0.041

0.044

Female

−3.866

0.507

−0.206

0.007

0.171

0.028

−0.030

0.674

−0.026

0.059

−0.902

0.055

BMI

1.818

0.003

0.007

0.353

−0.008

0.303

0.004

0.543

0.004

0.002

0.063

0.182

Grip strength

–

–

–

–

–

–

−0.011

0.002

–

–

–

–

Duration, years

−0.162

0.537

−0.005

0.154

0.005

0.134

0.002

0.496

−0.001

0.037

−0.010

0.647

DAS28

0.462

0.742

−0.006

0.766

0.009

0.660

−0.019

0.245

−0.001

0.721

−0.012

0.917

HAQ

–

–

−0.007

0.899

−0.001

0.981

0.030

0.498

–

–

–

–

HCQ

–

–

–

–

–

–

–

–

0.021

0.071

–

–

TWH

–

–

–

–

–

–

–

–

–

–

0.861

0.014

  1. Multivariable linear regression analysis was performed to identify potential factors associated with HRpQCT parameters at the distal tibia. Results for different parameters are presented in separate columns. β β-coefficient, TWH tripterygium wilfordii Hook