Referral to EGD Median (Q1, Q3) | No referral to EGD Median (Q1, Q3) | p* | |
---|---|---|---|
Age | 63 (52, 70.5) | 63 (53, 72) | 0.759 |
Disease duration | 11 (7, 20) | 10 (6,16) | 0.086 |
mRSS | 3 (0, 8) | 2 (0, 6) | 0.009 |
FVC | 98 (85, 109) | 97 (85, 110) | 0.813 |
BMI | 23.7 (21.4–26.7) | 23.4 (21, 27) | 0.712 |
Hemoglobin | 13.1 (12, 14.2) | 13.3 (12.4, 14.1) | 0.118 |
ESR | 16 (9, 26) | 12 (6, 22) | 0.013 |
n (%) | n (%) | p# | |
Subset of SSc | Diffuse 38 (24.4) Limited 118 (75.6) | Diffuse 156 (25.2) Limited 464 (74.8) | 0.836 |
Heartburn | 105 (60.7) | 207 (29) | < 0.001 |
Regurgitation | 41 (23.7) | 78 (10.9) | < 0.001 |
Dysphagia | 65 (38.5) | 112 (15.6) | < 0.001 |
Vomiting | 10 (5.9) | 22 (3.1) | 0.074 |
Esophageal symptoms | 109 (72.2) | 283 (43.5) | < 0.001 |
Stomach symptoms | 66 (44.3) | 139 (21.4) | < 0.001 |
Barrett’s esophagus | 17 (10.1) | 5 (0.7) | < 0.001 |
PPI therapy | 76 (62.3) | 18 (81.8) | 0.077 |
Digital ulcers | 16 (16) | 65 (15) | 0.811 |
Joint contractures | 46 (31.1) | 226 (35.1) | 0.354 |
UCLA GIT 2.0 subscales | Median (Q1, Q3) | Median (Q1, Q3) | p* |
Reflux | 0.50 (0.13, 0.88) | 0.14 (0.00, 0.50) | < 0.001 |
Distention/bloating | 0.75 (0.25, 1.46) | 0.25 (0.00, 1.00) | < 0.001 |
Fecal soilage | 0.00 (0.00, 1.00) | 0.00 (0.00, 0.00) | 0.067 |
Diarrhea | 0.00 (0.00, 0.50) | 0.00 (0.00, 0.50) | 0.028 |
Social functioning | 0.33 (0.00, 0.60) | 0.00 (0.00, 0.33) | < 0.001 |
Emotional wellbeing | 0.11 (0.00, 0.75) | 0.00 (0.00, 0.22) | < 0.001 |
Constipation | 0.25 (0.00, 0.75) | 0.00 (0.00, 0.50) | 0.004 |
Total score of UCLA GIT 2.0 | 0.35 (0.17, 0.70) | 0.19 (0.05, 0.44) | < 0.001 |