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Table 3 Comparison of patient data from visits in which EGD was recommended (n = 169) vs. data from visits in which EGD was not recommended (n = 740)

From: Performance of the UCLA Scleroderma Clinical Trials Consortium Gastrointestinal Tract 2.0 instrument as a clinical decision aid in the routine clinical care of patients with systemic sclerosis

  Referral to EGD
Median (Q1, Q3)
No referral to EGD
Median (Q1, Q3)
p*
Age 63 (52, 70.5) 63 (53, 72) 0.759
Disease duration 11 (7, 20) 10 (6,16) 0.086
mRSS 3 (0, 8) 2 (0, 6) 0.009
FVC 98 (85, 109) 97 (85, 110) 0.813
BMI 23.7 (21.4–26.7) 23.4 (21, 27) 0.712
Hemoglobin 13.1 (12, 14.2) 13.3 (12.4, 14.1) 0.118
ESR 16 (9, 26) 12 (6, 22) 0.013
  n (%) n (%) p#
Subset of SSc Diffuse 38 (24.4)
Limited 118 (75.6)
Diffuse 156 (25.2)
Limited 464 (74.8)
0.836
Heartburn 105 (60.7) 207 (29) < 0.001
Regurgitation 41 (23.7) 78 (10.9) < 0.001
Dysphagia 65 (38.5) 112 (15.6) < 0.001
Vomiting 10 (5.9) 22 (3.1) 0.074
Esophageal symptoms 109 (72.2) 283 (43.5) < 0.001
Stomach symptoms 66 (44.3) 139 (21.4) < 0.001
Barrett’s esophagus 17 (10.1) 5 (0.7) < 0.001
PPI therapy 76 (62.3) 18 (81.8) 0.077
Digital ulcers 16 (16) 65 (15) 0.811
Joint contractures 46 (31.1) 226 (35.1) 0.354
UCLA GIT 2.0 subscales Median (Q1, Q3) Median (Q1, Q3) p*
Reflux 0.50 (0.13, 0.88) 0.14 (0.00, 0.50) < 0.001
Distention/bloating 0.75 (0.25, 1.46) 0.25 (0.00, 1.00) < 0.001
Fecal soilage 0.00 (0.00, 1.00) 0.00 (0.00, 0.00) 0.067
Diarrhea 0.00 (0.00, 0.50) 0.00 (0.00, 0.50) 0.028
Social functioning 0.33 (0.00, 0.60) 0.00 (0.00, 0.33) < 0.001
Emotional wellbeing 0.11 (0.00, 0.75) 0.00 (0.00, 0.22) < 0.001
Constipation 0.25 (0.00, 0.75) 0.00 (0.00, 0.50) 0.004
Total score of UCLA GIT 2.0 0.35 (0.17, 0.70) 0.19 (0.05, 0.44) < 0.001
  1. Statistically significant results are highlighted in bold font
  2. *Mann-Whitney U test, #Chi-square test
  3. mRSS modified Rodnan skin score, FVC forced vital capacity, BMI body mass index, Hb hemoglobin, ESR erythrocyte sedimentation rate, PPI proton pump inhibitors