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Table 3 Comparison of patient data from visits in which EGD was recommended (n = 169) vs. data from visits in which EGD was not recommended (n = 740)

From: Performance of the UCLA Scleroderma Clinical Trials Consortium Gastrointestinal Tract 2.0 instrument as a clinical decision aid in the routine clinical care of patients with systemic sclerosis

 

Referral to EGD

Median (Q1, Q3)

No referral to EGD

Median (Q1, Q3)

p*

Age

63 (52, 70.5)

63 (53, 72)

0.759

Disease duration

11 (7, 20)

10 (6,16)

0.086

mRSS

3 (0, 8)

2 (0, 6)

0.009

FVC

98 (85, 109)

97 (85, 110)

0.813

BMI

23.7 (21.4–26.7)

23.4 (21, 27)

0.712

Hemoglobin

13.1 (12, 14.2)

13.3 (12.4, 14.1)

0.118

ESR

16 (9, 26)

12 (6, 22)

0.013

 

n (%)

n (%)

p#

Subset of SSc

Diffuse 38 (24.4)

Limited 118 (75.6)

Diffuse 156 (25.2)

Limited 464 (74.8)

0.836

Heartburn

105 (60.7)

207 (29)

< 0.001

Regurgitation

41 (23.7)

78 (10.9)

< 0.001

Dysphagia

65 (38.5)

112 (15.6)

< 0.001

Vomiting

10 (5.9)

22 (3.1)

0.074

Esophageal symptoms

109 (72.2)

283 (43.5)

< 0.001

Stomach symptoms

66 (44.3)

139 (21.4)

< 0.001

Barrett’s esophagus

17 (10.1)

5 (0.7)

< 0.001

PPI therapy

76 (62.3)

18 (81.8)

0.077

Digital ulcers

16 (16)

65 (15)

0.811

Joint contractures

46 (31.1)

226 (35.1)

0.354

UCLA GIT 2.0 subscales

Median (Q1, Q3)

Median (Q1, Q3)

p*

Reflux

0.50 (0.13, 0.88)

0.14 (0.00, 0.50)

< 0.001

Distention/bloating

0.75 (0.25, 1.46)

0.25 (0.00, 1.00)

< 0.001

Fecal soilage

0.00 (0.00, 1.00)

0.00 (0.00, 0.00)

0.067

Diarrhea

0.00 (0.00, 0.50)

0.00 (0.00, 0.50)

0.028

Social functioning

0.33 (0.00, 0.60)

0.00 (0.00, 0.33)

< 0.001

Emotional wellbeing

0.11 (0.00, 0.75)

0.00 (0.00, 0.22)

< 0.001

Constipation

0.25 (0.00, 0.75)

0.00 (0.00, 0.50)

0.004

Total score of UCLA GIT 2.0

0.35 (0.17, 0.70)

0.19 (0.05, 0.44)

< 0.001

  1. Statistically significant results are highlighted in bold font
  2. *Mann-Whitney U test, #Chi-square test
  3. mRSS modified Rodnan skin score, FVC forced vital capacity, BMI body mass index, Hb hemoglobin, ESR erythrocyte sedimentation rate, PPI proton pump inhibitors