Table 4 Factors associated with referral to EGD (multivariable generalized linear mixed effects models, GLMM). Statistically significant results are highlighted in bold font
Multivariable GLMM | |||||
|---|---|---|---|---|---|
Parameters | Models* | OR | 95% CI | p | AUC (95% CI) |
Age | Model 1 | 0.99 | 0.97–1.01 | 0.269 | 0.75 (0.69–0.80) |
Sex | 0.66 | 0.33–1.33 | 0.242 | ||
Disease duration | 1.00 | 0.98–1.02 | 0.926 | ||
SSc subset | 1.27 | 0.67–2.40 | 0.471 | ||
mRSS | 1.05 | 1.00–1.10 | 0.030 | ||
Hb | 0.89 | 0.74–1.07 | 0.218 | ||
PPI | 0.80 | 0.49–1.30 | 0.363 | ||
BMI | 1.03 | 0.97–1.09 | 0.294 | ||
FVC | 1.00 | 0.99–1.01 | 0.948 | ||
ESR | 1.00 | 0.99–1.02 | 0.943 | ||
Barrett’s esophagus | 24.4 | 2.43–245.18 | 0.007 | ||
Heartburn | Model 2 | 2.23 | 1.35–3.69 | 0.002 | 0.71 (0.65–0.76) |
Regurgitation | 2.09 | 1.14–3.81 | 0.017 | ||
Dysphagia | 3.01 | 1.79–5.05 | < 0.001 | ||
Vomiting | 1.98 | 0.62–6.25 | 0.247 | ||
Esophageal symptoms | Model 3 | 1.91 | 1.14–3.18 | 0.013 | 0.68 (0.62–0.74) |
Stomach symptoms | 2.12 | 1.24–3.61 | 0.006 | ||
Reflux subscale | Model 4 | 1.86 | 1.19–2.90 | 0.006 | 0.68 (0.62–0.74) |
Distention/bloating subscale | Model 5 | 1.50 | 1.12–2.01 | 0.007 | 0.70 (0.65–0.76) |
Social functioning | Model 6 | 2.57 | 1.56–4.23 | < 0.001 | 0.65 (0.59–0.71) |
Emotional wellbeing | Model 7 | 1.32 | 0.80–2.19 | 0.274 | 0.68 (0.62–0.74) |
Total UCLA GIT 2.0 score | Model 8 | 2.16 | 1.21–3.83 | 0.009 | 0.64 (0.58–0.70) |