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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Cold-inducible RNA-binding protein (CIRP) potentiates uric acid-induced IL-1β production

Fig. 7

CIRP-induced NLRP3 expression in neutrophils. CIRP (300 ng/ml, for 30 min)-primed neutrophils were pretreated with or without MCC950) for 30 min and stimulated with MSU (200 μg/mL) for 18 h. Cellular lysates were analyzed by western blotting using anti-NLRP3 antibodies. β-actin was the loading control. Two experiments were performed using different neutrophils, and a representative result is shown

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