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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses

Fig. 3

Upregulation of LFA-1 expression in the neutrophils of patients with AAV. (A) Expression of LFA-1 in (a) neutrophils, (b) monocytes, and (c) lymphocytes. (B) Temporal change in LFA-1 expression in the neutrophils of (a) non-responder and (b) responder AAV patients. *P < 0.05 using the (A) Kruskal-Wallis test or (B) Wilcoxon’s signed-rank test. LFA-1, lymphocyte function-associated antigen-1; AAV, ANCA-associated vasculitis; HC, healthy control; MPA, microscopic polyangiitis; GPA, granulomatosis with polyangiitis; EGPA, eosinophilic granulomatosis with polyangiitis; GCA, giant cell arteritis; TAK, Takayasu arteritis; wk., week; NS, not significant

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