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Table 2 Comparison of the most abundantly expressed proteins in the inflammatory foci of CLE and DM skin lesions

From: Proteome study of cutaneous lupus erythematosus (CLE) and dermatomyositis skin lesions reveals IL-16 is differentially upregulated in CLE

Numbers of proteins CLE/HC DM/HC CLE/DM
Interleukin-16 (IL-16) (x fold) 12 1 12
IFN regulated and associated proteins, high in both LE and DM (x fold)
 IFIT1 71 57 1.2
 IFIT3 70 46 1.3
 DDX58 48 33 1.5
 ISG15 48 30 1.6
 OAS2 36 21 1.7
 MX1 31 16 2
 MX2 29 14 2
 STAT1 29 16 1.9
 OAS3 28 33 0.83
 EIF2AK2 23 15 1.5
 IFI44L 18 18 1
 IFIT2 13 11 1.2
 DDX21 6 6.5 1
 IFI16 6 4.5 1.1
 ADAR 7.3 5 1.4
IFN-regulated and associated proteins, high in LE but low in DM (x fold)
 MNDA 31 Low* 31
 PTPN6 24 Low* 24
 DDX60 18 Low* 18
 STAT2 14 Low* 3.8
 ZC3HAV1 14 Low* 7
 OASL 14 Low* 14
 IFI44 10 Low* 1.6
 IFIT5 8 Low* 2
 OAS1 8 Low* 8
Antigen processing and transport (x fold)
 TAP1 18.5 10 1.9
 TAP2 24 19 1.3
 TAPBP 5.4 1.1  
Aminoacyl-tRNA synthases and other enzymes (x fold)
 WARS 90 55 1.6
 TARS 13 10 1.3
 TYMP 9.4 9 1
 ACLY 28 9 3
 GOT1 8 8 1
  1. *Detected as 5 or fewer peptides, therefore regarded as an unreliable result