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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways

Fig. 1

Fargesin attenuates cartilage damage and synovitis in CIOA. (a, f) Cartilage degradation assessed by Safranin O and Fast Green staining. Dotted lines represent tide line. Scale bar: 100 μm (top) and 40 μm (bottom). (b, g) OARSI score was evaluated in CIOA mice treated with vehicle or fargesin. (c, h) Cartilage thickness was evaluated using ratio between calcified cartilage (CC) and hyaline cartilage (HC). (d, i) H&E staining in CIOA mice treated with vehicle or fargesin. Scale bar: 100 μm. (e, j) Synovitis score quantification in CIOA mouse synovium treated with vehicle or fargesin (n = 4)

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Arthritis Research & Therapy

ISSN: 1478-6362

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