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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Decreased microRNA-155 in Behcet’s disease leads to defective control of autophagy thereby stimulating excessive proinflammatory cytokine production

Fig. 5

MiR-155 regulates autophagy through Akt/mTOR pathway. DCs from normal controls (n=8) and active BD patients (n=8) were assessed. After 48 h, DCs were stimulated with 100ng/mL LPS for 24 h. a Total levels of Akt and mTOR, together with phosphorylation levels of Akt and mTOR in DCs were determined by Western blotting. bc Quantification of expression levels of p-Akt/Akt and p-mTOR/mTOR proteins. *p<0.05, **p<0.01

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