Fig. 3

The proportion of Tregs is decreased in the dermis of BLM-treated Fli1^+/− mice. Wild-type (WT) and Fli1^+/− mice were treated with bleomycin (BLM) for a week. The percentages of IFN-γ-, IL-4-, and IL-17A-producing CD4⁺ T cells and CD4⁺CD25⁺Foxp3⁺ Tregs in the dermis were determined by flow cytometry. Flow cytometry profiles are representative of 5-9 individual animals from at least 2 separate experiments. Each graph indicates mean ± SEM of the indicated parameters. *P < 0.05