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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Fli1 deficiency suppresses RALDH1 activity of dermal dendritic cells and related induction of regulatory T cells: a possible role in scleroderma

Fig. 3

The proportion of Tregs is decreased in the dermis of BLM-treated Fli1+/− mice. Wild-type (WT) and Fli1+/ mice were treated with bleomycin (BLM) for a week. The percentages of IFN-γ-, IL-4-, and IL-17A-producing CD4+ T cells and CD4+CD25+Foxp3+ Tregs in the dermis were determined by flow cytometry. Flow cytometry profiles are representative of 5-9 individual animals from at least 2 separate experiments. Each graph indicates mean ± SEM of the indicated parameters. *P < 0.05

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