Skip to main content

Table 2 Differences in baseline scoresa

From: Opioid users show worse baseline knee osteoarthritis and faster progression of degenerative changes: a retrospective case-control study based on data from the Osteoarthritis Initiative (OAI)

 

Unadjustedc

Adjustedd

Score

Coef.b

95% CI

Pe

Coef.b

95% CI

Pe

WORMSf

      

 Total

7.2

5.4, 9.1

< 0.001

7.1

5.5, 8.8

< 0.001

 Cartilage

2.6

1.8, 3.5

< 0.001

2.6

1.8, 3.4

< 0.001

 Meniscus

1.9

1.3, 2.4

< 0.001

1.9

1.4, 2.4

< 0.001

 BMEL

0.6

0.2, 0.9

0.006

0.5

0.2, 0.9

0.006

 Subchondral cyst

1.0

0.6, 1.4

< 0.001

0.9

0.6, 1.3

< 0.001

KOOSg

      

 QOL

−12.9

−16.7, −9.1

< 0.001

−12.2

−15.8, −8.5

< 0.001

 Symptom

−6.6

−8.8, −4.4

< 0.001

−6.0

−8.0, −3.8

< 0.001

 Pain

−10.0

−12.9, −7.1

< 0.001

−9.2

−12.1, −6.4

< 0.001

  1. aOpioid users, n = 181; controls, n = 362. bCoefficients indicate differences in scores between opioid users and controls. cUnadjusted linear regression models, reflecting raw baseline differences. dLinear regression models, adjusted for age, sex, body mass index, race, and baseline Kellgren-Lawrence grade. fSignificant P values are printed bold. eA higher WORMS score indicates worse structural knee damage. gKOOS scores range from 0 to 100, with lower KOOS scores reflecting worse reported knee problems. WORMS, Whole-Organ Magnetic Resonance Imaging score; KOOS, Knee injury and Osteoarthritis Outcome Score; BMEL, bone marrow edema-like lesions; QOL, quality of life; Coef., coefficient; 95% CI, 95% confidence interval