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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats

Fig. 7

Immunohistochemistry assay for a CD24 and SOX-9 in the nucleus pulposus in different groups. The number of chondrocyte-like cells was found by counting the number of SOX-9-positive staining cells. The thin red arrow indicates chondrocyte-like cells. b, c Immunohistological analysis showed that the expression of CD24 in the OVX+PLF+Dmab group was greater than that in the OVX+PLF group. There were fewer SOX-9-positive cells in the OVX+PLF+Dmab group than in the OVX+PLF group. Note: *P < 0.05, **P < 0.01; scale bars = 50 μm as indicated

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Arthritis Research & Therapy

ISSN: 1478-6362

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