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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: The heterogeneous human memory CCR6+ T helper-17 populations differ in T-bet and cytokine expression but all activate synovial fibroblasts in an IFNγ-independent manner

Fig. 3

All CCR6+ subpopulation from healthy controls and RA patients activate SF. Sorted CCR6+ subpopulations from healthy donors (A, 25,000 T cells) or treatment-naïve early RA patients (B, 4000–10,000 T cells) were cultured for 3 days together with SF upon stimulation with anti-CD3 and anti-CD28. Cytokines were measured in the culture supernatant on day 3 using ELISA. Data are shown as mean ± SEM of n = 6 healthy controls or n = 5 RA patients and representative of at least 2 independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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Arthritis Research & Therapy

ISSN: 1478-6362

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