Fig. 6

Metabolites differentially abundant between the two CRP patient groups. Among the 67 total metabolites identified through our multi-approach analysis on the discovery cohort (n = 128), eight metabolites were identified to have significant associations with the CRP group while controlling for confounding variables (regression coefficient for CRP, P < 0.05). A Metabolites with higher abundances in the high-CRP group: mannose, beta-hydroxyisovalerate, (14 or 15)-methylpalmitate (a17:0 or i17:0), erucate (22:1n9), 10-undecenoate (11:1n1), and N-acetylcitrulline. B Metabolites with higher abundances in the low-CRP group: serine and linoleoylcarnitine (C18:3)