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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: IgG and IgA autoantibodies against L1 ORF1p expressed in granulocytes correlate with granulocyte consumption and disease activity in pediatric systemic lupus erythematosus

Fig. 3

Presence of p40 protein in a subset of immune cells. A Summary of flow cytometry data in pSLE patients. B Summary of flow cytometry data in adult SLE patients. C Summary of flow cytometry data in healthy controls (HC). D Scatter plot of percent p40-positive CD66b+ cells in the PMN fraction versus SLEDAI at the time of blood draw in adult SLE patients. E Scatter plot of percent p40-positive CD66b+ cells in the PBMC fraction versus SLEDAI at the time of blood draw in adult SLE patients. F Relative expression of CD66b in neutrophils expressing p40 (p40+) compared to those without detectable p40 (p40−). G Anti-p40 mAb immunoblot of PBMC and PMN lysates from SLE and HC, as indicated. Identical cell equivalents of each (2.5 × 106) were loaded

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