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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: IgG and IgA autoantibodies against L1 ORF1p expressed in granulocytes correlate with granulocyte consumption and disease activity in pediatric systemic lupus erythematosus

Fig. 4

Markers of neutrophil death in pSLE patients and healthy controls. A Levels of MPO-DNA complexes in healthy controls (HC) and pediatric lupus patients with inactive (iSLE) and active (aSLE) disease. B Levels of NE-DNA complexes in the same patient groups. C Levels of calprotectin (S100A8/A9) in the same patient groups. D Correlation between MPO-DNA and NE-DNA complexes in patients with active disease. Statistical significance by Mann-Whitney U test and Wilcoxon, and correlation by Spearman’s correlation test

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